2/11/2024 0 Comments Physiologic dead space =V d V t = P A C O 2 − P e C O 2 P A C O 2 Ī common step is to then presume that the partial pressure of carbon dioxide in the end-tidal exhaled air is in equilibrium with that gas' tension in the blood that leaves the alveolar capillaries of the lung. The original formulation by Bohr, required measurement of the alveolar partial pressure P A. The volume of air that participates in gas exchange because it is in contact with perfused alveoli is the alveolar ventilation (V A V E V D physiological). The Bohr equation is used to quantify the ratio of physiological dead space to the total tidal volume, and gives an indication of the extent of wasted ventilation. Physiological dead space may be increased with lung disease, due to an increase in the alveolar component. It differs from anatomical dead space as measured by Fowler's method as it includes alveolar dead space. This is given as a ratio of dead space to tidal volume. The Bohr equation, named after Danish physician Christian Bohr (1855–1911), describes the amount of physiological dead space in a person's lungs. Not to be confused with the Bohr model or the Bohr effect.
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